for aprta FROZENIX

For Aortic Arch Repair

FROZENIX was designed specifically for the Frozen Elephant Trunk technique.

With a wide range of sizes, FROZENIX provides an optimal solution for the treatment of aortic aneurysm and dissection.

The system is simple and easy, allowing for a quick implant procedure.

The delivery system is intuitive and the softness of the graft material makes suturing easy.

The unique stent design balances flexibility and radial force, providing optimal long-term performance.

Caution: The products listed on this website are not cleared/approved in the United States.

>35,000 implants globally

KOL comments

Procedural Techniques

  • Mastering FROZENIX 4 Branched
    for Acute Aortic Dissection

  • Distal Anastomosis Technique Using
    FROZENIX 4 Branched

Case Study

Clinical Outcomes

  • 100%

    Thrombus formation in aortic aneurysm at 12 months *1

  • 94%

    Thrombus formation in aortic dissection at 12 months *1

  • 93.9%

    Shrinkage or no change of aneurysm size at 12 months *1

  • 94.4%

    Shrinkage or no change of false lumen size at 12 months *1

Reference
1. A new device as an open stent graft for extended aortic repair: a multicentre early experience in Japan. European Journal of Cardio-Thoracic Surgery 49 (2016) 1270–1278. doi:10.1093/ejcts/ezv310

Clinical Experience Overview

Article DOI N
H Ogino, Y Okita, N Uchida, et al. Comparative study of Japanese frozen elephant trunk device for open aortic arch repairs https://doi.org/10.1016/j.jtcvs.2021.03.079 369
A Yoshitake, O Kinoshita, T Gyoten et al. Ten-Year Single-Center Experience With a Japanese Frozen Elephant Trunk Graft (FROZENIX) for Treating Thoracic Aortic Disease in 435 Patients https://doi.org/10.1253/circj.CJ-25-0013 435
C Tokunaga, Y Kumagai, F Chubachi, et al. Total arch replacement using frozen elephant trunk technique with Frozenix for distal aortic arch aneurysms https://doi.org/10.1093/icvts/ivac038 121
Y Inoue, K Yoshida, Y Koda, et al. Efficacy of total arch replacement with frozen elephant trunk in patients with acute type A aortic dissection https://doi.org/10.1016/j.xjon.2025.07.002 370
Y Ikeno, K Yokawa, Y Koda, et al. The fate of the downstream aorta after open aortic repair for acute DeBakey type I aortic dissection:total arch replacement with elephant trunk technique versus non-total arch replacement https://doi.org/10.1093/ejcts/ezy381 267
H Yamamoto, T Kadohama, G Yamaura, et al. Total arch repair with frozen elephant trunk using the "zone 0 arch repair" strategy for type A acute aortic dissection https://doi.org/10.1016/j.jtcvs.2019.01.125 108
H Okamura, S Azuma, Y Kitada, et al. Outcomes of fenestrated frozen elephant trunk technique in 150 patients with acute type A aortic dissection https://www.jtcvstechniques.org/article/S2666-2507(24)00335-3/fulltext#fig3 150
M Usui, H Yoshino, K Akutsu, et al. Interfacility Transfer and Mortality in Patients With Type A Acute Aortic Dissection -Analysis of the Tokyo Acute Aortic Super-Network Database https://pubmed.ncbi.nlm.nih.gov/41669512/ ー

Caution: The products listed on this website are not cleared/approved in the United States.

Prior to using these devices, please review the Instructions for Use for a complete listing of indications, contraindications,
warnings, precautions, potential adverse events and directions for use.
Devices and configurations depicted may not be available in all countries. Check with your Japan
Lifeline representative for availability in your country.